RENAL MASS – HYPERNEPHROMA – RENAL CELL CARCINOMA


This was a 40 year old gentleman with obesity and systemic hypertension . He was on tab losartan 50 mgm once daily and his B.P. was well controlled.

He came for complaints of frank hematuria and passing  clots of blood since 5 AM and right loin pain since 9 AM .

His ultrasound showed the following  :

The urinary bladder showed ? mass lesion at first look.

KIDNEY  HYPERNEPHROMA_2 KIDNEY  HYPERNEPHROMA_3 KIDNEY  HYPERNEPHROMA_4

With change of position this ” mass ” was seen to roll within the urinary bladder , suggestive of blood clot.

KIDNEY  HYPERNEPHROMA_7 KIDNEY  HYPERNEPHROMA_6 KIDNEY  HYPERNEPHROMA_5

 

The right kidney is shown below. A solid mass is  seen in the lower pole region.

KIDNEY  HYPERNEPHROMA_8

 

The mass shows increased vascularity on Power Doppler.

 

KIDNEY  HYPERNEPHROMA_9

The mass measurements are given below.

 

KIDNEY  HYPERNEPHROMA_10

 

 

 

 

KIDNEY  HYPERNEPHROMA_11

GLASS BODY RECONSTRUCTION shows increased vascularity.

 

 

KIDNEY  HYPERNEPHROMA_12 KIDNEY  HYPERNEPHROMA_14

The left kidney appears to be normal.

KIDNEY  HYPERNEPHROMA_18

 

KIDNEY  HYPERNEPHROMA_19 KIDNEY  HYPERNEPHROMA_20 KIDNEY  HYPERNEPHROMA_21

 

 

The diagnosis offered was HYPERNEPHROMA ( RENAL CELL CARCINOMA )

The patient underwent further investigations to rule out any spread and was found to have a localised tumour and was taken up for robotic surgery . He underwent surgery successfully . His histopatholgy came os RENAL CELL CARCINOMA – CLEAR CELL TYPE , with no involvement of the renal vein , ureter or renal capsule. anand 1 anand 2

The following references could be useful.

http://emedicine.medscape.com/article/281340-overview

https://en.wikipedia.org/wiki/Renal_cell_carcinoma

http://www.nlm.nih.gov/medlineplus/ency/article/000516.htm

Renal cell carcinoma (RCC, also known as hypernephroma, Grawitz tumor, renal adenocarcinoma) is a kidney cancer that originates in the lining of the proximal convoluted tubule, a part of the very small tubes in the kidney that transport waste molecules from the blood to the urine.

RCC is the most common type of kidney cancer in adults, responsible for approximately 90-95% of cases. 

It has been described as one of the deadliest of cancers affecting the genitourinary tract.

Initial treatment is most commonly either partial or complete removal of the affected kidney(s) and remains the mainstay of curative treatment. 

Where the cancer has not metastasised (spread to other organs) or burrowed deeper into the tissues of the kidney the 5-year survival rate is 60-70%, but this is lowered considerably when the cancer has spread. It is relatively resistant to radiation therapy and chemotherapy, although some cases respond to targeted therapies such assunitinib, temsirolimus, bevacizumab, interferon alfa and sorafenib which have improved the outlook for RCC.

In this patient  the increased vascularity is  brought out very well by glass body imaging . Clots of blood seen in the urinary bladder gave the false impression of a mass lesion in the bladder initially.The importance of a dynamic study of turning the patient to the sides should always be remembered.

In this blog ” Looking through a transducer ” , this is the third case of renal mass with increased vascularity . Two were confirmed to have hypernephroma and one was lost for follow up.

Please visit our earlier posts also.

https://kriznanultrasoundimages.com/2014/01/05/renal-mass-2/

https://kriznanultrasoundimages.com/2013/05/26/adult-renal-mass-colour-doppler-and-3d-images/

7 thoughts on “RENAL MASS – HYPERNEPHROMA – RENAL CELL CARCINOMA

  1. Due to your immense dedication & knowledge you have once again gave life for a family. I think you should get ready to publish a book-“Thro The Transducer In Semi Urban set up”

    Like

  2. Wonderful case study. The images were great as well. I enjoyed seeing your investigative skills. Many Sonographers would have just assumed it was a mass in the bladder and not change patient position to see if mass rolled.

    Like

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